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Kinetics of DEN-specific IgA, IgM, and IgG subclass responses in DEN patients with various disease severity, over a period of 2 weeks after onset of fever. Results are expressed as mean ratios. □, IgM response; ■, IgA response; ▿, IgG1 response; ●, IgG2 response; ○, IgG3 response; ▾, IgG4 response.
