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. 2021 Nov 26;126(4):673–688. doi: 10.1038/s41416-021-01521-8
Population Intervention Comparison Outcomes

Women who are at average risk of breast cancer:

• 45–49 years

• 50–69 years

• 70–74 years

Annual, biennial or triennial mammography screening (film or digital) Another interval (annual, biennial or triennial)

1. Breast cancer mortality

2. Incidence of interval cancer

3. Stage of breast cancer

4. Radiation induced breast cancers

5. Deaths due to radiation induced breast cancers

6. Quality of life

7. False positive related adverse effects

8. Overdiagnosis