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. 2022 Feb 17;12:2711. doi: 10.1038/s41598-022-04980-y

Figure 1.

Figure 1

Analysis of transcriptomes of CSCs converted from miPSCs by RNA-seq. (A) Schematic chart of conversion of miPSCs into CSCs, converted cells were prepared by culturing miPSCs in 50% CM, then cells were transplanted into mice and CSCs were isolated from the primary culture of the tumors. (B) A heat map of gene expression in miPSCs, miPS-PK8cm, and miPS-PK8cmP cells. (C) A Venn diagram showing the differentially expressed genes in miPS-PK8cm and miPS-PK8cmP cells when compared with those in miPSCs and the bar graph depicting the number of up- and downregulated genes in miPS-PK8cm and miPS-PK8cmP cells when compared with those in miPSCs.