Figure 6. Plaque reduction assay for HCoV-229E.
A. Titration of HCoV-229E in the RD cell line. B. Determination of EC50 value for remdesivir against HCoV-229E in plaque assay. C. Determination of EC50 value for GC-376 against HcoV-229E in plaque assay. D. EC50 curve fitting for remdesivir obtained in GraphPad Prism 8. E. EC50 curve fitting for GC-376 obtained in GraphPad Prism 8. F. Titration of HcoV-229E in the Huh-7 cell line. G. Titration of HCoV-229E in the MRC-5 cell line. The images are representatives of three independent repeats.