. 2022 Feb 4;8:770471. doi: 10.3389/fmolb.2021.770471

TABLE 2.

Effect of treatment with Phα1β or Morphine on formalin-induced brain activation: comparison between brain regions according to the cerebral hemisphere. Values represent mean ± S. E. M. of¹⁸F-FDG uptake normalised by uptake in the intrathecal PBS group.

Region	Ipsilateral		Contralateral
Region	Phα1β	Morphine	Phα1β	Morphine
AcbCore/Shell	93.78 ⁺ 3.52	94.46 ⁺ 3.32	94.47 ⁺ 3.40	91.18 ⁺ 3.16
Amygdala	100.87 ⁺ 8.63	93.22 ⁺ 5.60	100.39 ⁺ 8.88	89.11 ⁺ 4.59
CaudatePutamen	95.56 ⁺ 5.67	92.77 ⁺ 3.11	96.43 ⁺ 5.49	94.32 ⁺ 3.51
CortexAuditory	102.03 ⁺ 5.14	98.01 ⁺ 4.74	98.51 ⁺ 4.29	96.16 ⁺ 4.16
CortexCingulate	97.42 ⁺ 3.74	96.73 ⁺ 4.05	89.04 ⁺ 3.04	91.16 ⁺ 4.58
CortexEntorhinal	95.16 ⁺ 4.69	90.73 ⁺ 4.86	99.55 ⁺ 4.69	89.46 ⁺ 4.60
CortexFrontalAssociation ^a	98.87 ⁺ 6.36	98.20 ⁺ 6.21
CortexFrontal ^a	101.43 ⁺ 4.23	99.61 ⁺ 5.05
CortexInsular	100.70 ⁺ 7.86	94.36 ⁺ 3.51	98.31 ⁺ 5.02	94.36 ⁺ 3.51
CortexMedialPrefrontal	96.40 ⁺ 3.57	97.60 ⁺ 5.23	94.27 ⁺ 4.26	97.64 ⁺ 6.09
CortexMotor	100.39 ⁺ 4.15	96.91 ⁺ 2.99	91.49 ⁺ 3.19	92.07 ⁺ 3.98
CortexOrbitofrontal	98.62 ⁺ 5.59	97.39 ⁺ 3.21	100.79 ⁺ 3.71	98.90 ⁺ 3.39
CortexParA	100.71 ⁺ 510	99.16 ⁺ 4.89	98.72 ⁺ 4.57	101.93 ⁺ 4.14
CortexRetrosplenial	98.42 ⁺ 5.05	97.55 ⁺ 5.10	96.89 ⁺ 4.94	96.25 ⁺ 3.98
CortexSomatosensory	98.13 ⁺ 4.50	94.74 ⁺ 3.96	94.73 ⁺ 3.38	94.50 ⁺ 4.51
CortexVisual	100.01 ⁺ 5.18	100.63 ⁺ 4.86	98.52 ⁺ 4.17	100.60 ⁺ 3.96
HippocampusAnteroDorsal	98.35 ⁺ 3.79	98.23 ⁺ 4.20	100.72 ⁺ 3.81	101.34 ⁺ 3.87
HippocampusPosterior	96.48 ⁺ 6.13	96.83 ⁺ 5.47	97.66 ⁺ 5.01	94.61 ⁺ 3.00
Hypothalamus	95.01 ⁺ 4.20	95.38 ⁺ 4.18	97.06 ⁺ 4.44	95.29 ⁺ 5.31
Olfactory	93.92 ⁺ 5.09	90.52 ⁺ 4.72	98.94 ⁺ 4.44	93.69 ⁺ 2.76
SuperiorColliculus	96.63 ⁺ 4.23	97.53 ⁺ 4.88	96.48 ⁺ 4.14	98.49 ⁺ 4.16
Midbrain	99.29 ⁺ 3.92	98.42 ⁺ 4.33	99.66 ⁺ 5.70	98.19 ⁺ 4.49
VTA	97.03 ⁺ 4.89	104.24 ⁺ 6.14	95.44 ⁺ 4.60	97.71 ⁺ 5.66
CB-grey	95.91 ⁺ 4.70	101.00 ⁺ 5.40	98.23 ⁺ 5.53	103.29 ⁺ 6.00
CB-white	96.14 ⁺ 4.34	100.97 ⁺ 4.32	96.74 ⁺ 4.71	100.57 ⁺ 5.23
InferiorColliculus	97.53 ⁺ 5.04	96.22 ⁺ 3.90	96.10 ⁺ 3.63	99.96 ⁺ 5.33
ThalamusWhole	95.79 ⁺ 3.22	96.28 ⁺ 4.38	97.26 ⁺ 3.97	96.28 ⁺ 4.38
Pituitary ^a	98.44 ⁺ 6.32	97.90 ⁺ 9.98
CB-bloodflow ^a	98.52 ⁺ 4.93	98.78 ⁺ 4.34
CentralCanal-PAG ^a	95.70 ⁺ 3.90	97.40 ⁺ 4.95
Pons ^a	97.3 ⁺ 5.28	100.92 ⁺ 5.93
Septum ^a	97.32 ⁺ 4.24	95.54 ⁺ 3.84
Medulla ^a	97.86 ⁺ 6.43	99.87 ⁺ 4.94

Regions located in a central plane between the two cerebral hemispheres. They are not categorised as right or left by the analysis software, although they are presented as ipsilateral in the table. The definition of contra or ipsilateral was made in reference to the right paw where formalin or PBS, was administered.