Figure 2.

Histology and HI score of the colon. Histology of the mice colon in the (A) DSS, (B) normal, (C) anti-TNF-α and (D) 5-ASA groups as assessed by H&E staining. Magnification, ×200. Arrows indicate crypts, long-tailed arrows indicate erosion or ulcerated intestinal mucosa, and hollow arrows indicate inflammatory cell infiltration. (E) HI score of the mouse colonic mucosa in the four groups. Anti-TNF-α and 5-ASA decreased the HI score of the colonic mucosa in mice with DSS-induced colitis. *P<0.05 vs. DSS. DSS, dextran sulfate sodium; HI, histological index; 5-ASA, 5-aminosalicyclic acid.