Table III.
Association between FH of BC and genetic test results.
| Groups | ||||
|---|---|---|---|---|
|
|
||||
| Genetic test results | FH status | CG | SG | P-value |
| Negative | FH of BC | 0.022 | ||
| No | 33 (50.0) | 11 (84.6) | ||
| Yes | 33 (50.0) | 2 (15.4) | ||
| FH of any cancer | 0.370 | |||
| No | 8 (12.0) | 3 (23.0) | ||
| Yes | 58 (88.0) | 10 (77.0) | ||
| VUS | FH of BC | 0.620 | ||
| No | 46 (56.1) | 10 (50.0) | ||
| Yes | 36 (43.9) | 10 (50.0) | ||
| FH of any cancer | 0.170 | |||
| No | 14 (17.0) | 1 (5.0) | ||
| Yes | 68 (83.0) | 19 (95.0) | ||
| Negative, PV+VUS | Only patients with FH of BC | 0.045 | ||
| Negative | 33 (36.7) | 2 (11.8) | ||
| PV+VUS | 57 (63.3) | 15 (88.2) | ||
Data are presented as the n (%). BC, breast cancer; FH, family history; SG, study group; CG, control group; VUS, variant of uncertain significance; PV, pathogenic variant.