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. 2022 Feb 7;25(4):115. doi: 10.3892/mmr.2022.12631

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Copyright: © Wang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 3. — Overexpression of PTX3 inhibits the invasion of HTR-8/SV neo and JEG3 cells. Cell invasion in (A) HTR-8/SV neo and (B) JEG3 cells following PTX3 overexpression were assessed by using a Transwell invasion assay. The mRNA expression of MMP2 and MMP9 in (C) HTR-8/SV neo and (D) JEG3 cells following PTX3 overexpression was detected via reverse transcription-quantitative PCR. The protein expression of MMP2 and MMP9 in (E) HTR-8/SV neo and (F) JEG3 cells following PTX3 overexpression was determined using western blotting. **P<0.01, ***P<0.001 vs. Control; ^##P<0.01, ^###P<0.001 vs. Ov-NC. PTX3, pentraxin 3; Ov, overexpression vector; NC, negative control.