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. 2022 Feb 7;25(4):115. doi: 10.3892/mmr.2022.12631

Figure 5.

Figure 5.

IL-1Ra suppresses the inhibitory effects of PTX3 overexpression on the proliferation and cell cycle of HTR-8/SV neo and JEG3 cells. The proliferation of (A) HTR-8/SV neo and (B) JEG3 cells treated with Ov-PTX3 and IL-1Ra was tested by Cell Counting Kit-8 assay. Cell cycle distributions of (C) HTR-8/SV neo and (D) JEG3 cells treated with Ov-PTX3 and IL-1Ra were assessed by flow cytometry. *P<0.05, ***P<0.001 vs. Control; #P<0.05, ##P<0.01, ###P<0.001 vs. Ov-PTX3. IL-1Ra, interleukin-1 receptor antagonist; PTX3, pentraxin 3; Ov, overexpression vector.