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. Author manuscript; available in PMC: 2023 Jan 20.
Published in final edited form as: Tuberculosis (Edinb). 2022 Jan 20;132:102168. doi: 10.1016/j.tube.2022.102168

Table 1.

Concentration (μM) required to inhibit Mycobacteria 50% compared to a kanamycin control.

IC50 (μM)
Compounda M. abs M. tb M. smeg
Kanamycin (control) 29 ± 6 14 ± 2 5 ± 2
11426093 graphic file with name nihms-1774117-t0009.jpg 342 ± 116 NT NT
11826433 graphic file with name nihms-1774117-t0010.jpg 267 ± 79 NT NT
11426122 graphic file with name nihms-1774117-t0011.jpg 452 ± 2 NT NT
11926210 graphic file with name nihms-1774117-t0012.jpg 262 ± 42 NT NT
11926211 graphic file with name nihms-1774117-t0013.jpg 315b NT NT
11926223 graphic file with name nihms-1774117-t0014.jpg 478b NT NT
10726016 graphic file with name nihms-1774117-t0015.jpg NI 216b 14b
10726028 graphic file with name nihms-1774117-t0016.jpg NI 315b 109b
a

Results shown are the means ± SDs from 1 to 11 independent experiments with each independent assay always being performed with technical triplicate wells.

b

Experiments were only performed once. NI, no inhibitory activity; NT, not tested.