Table 1. Kinetic Parameters Derived from ThT Experiments Shown in Figure 1a.
| sample | Imax (A.U.) | tlag (min) | t1/2 (min) | kapp (min–1) | τ (min) |
|---|---|---|---|---|---|
| Aβ1–40 20 μM | 26.2 ± 0.1 | 407.2 ± 1.3 | 457.4 ± 1.2 | 10·10–3 ± 1.0·10–4 | 100.4 ± 6.2 |
| Aβ1–40 20 μM/Cu2+ 1:1 | 11.9 ± 0.1 | 129.7 ± 0.8 | 141.0 ± 0.5 | 4.4·10–2 ± 9.5·10–4 | 22.5 ± 9.1 |
| Aβ1–40 20 μM/Semax 1:1 | 25 ± 0.1 | 372.8 ± 2.3 | 430.9 ± 1.5 | 8.6·10–3 ± 9.9·10–5 | 116.2 ± 10.2 |
| Aβ1–40 20 μM/Semax 1:5 | 18.3 ± 0.1 | 577.8 ± 3.2 | 601.5 ± 2.7 | 2.1·10–2 ± 1.0·10–3 | 47.3 ± 7.4 |
| Aβ1–40 20 μM/Cu2+/Semax 1:1:1 | 25.7 ± 0.1 | 344.6 ± 2.5 | 412.2 ± 2.0 | 7.4·10–3 ± 9.6·10–5 | 135.1 ± 9.7 |
| Aβ1–40 20 μM/Cu2+/Semax 1:1:5 | 15.5 ± 0.2 | 544.4 ± 7.3 | 582.2 ± 6.1 | 1.3·10–2 ± 9.4·10–4 | 75.6 ± 13.1 |
a
ThT curves were fitted by using
the equation 
. Lag time was calculated as tlag = t1/2 –
2τ,
and kapp was given by 1/τ. Results
are the average of three independent experiments.