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. 2022 Jan 26;13(4):486–496. doi: 10.1021/acschemneuro.1c00707

Table 2. Kinetic Parameters Derived from ThT Experiments Shown in Figure 4a.

sample Imax (A.U.) tlag (min) t1/2 (min) k (min–1) τ (min)
1–40 20 μM 12.7 ± 0.2 239.0 ± 2.5 439.0 ± 2.8 2.5·10–2 ± 1.2·10–3 40.0 ± 2.3
1–40 20 μM/Cu2+ 1:1 21.5 ± 0.1 814,5 ± 3.2 986.9 ± 3.5 2.8·10–3 ± 1.0·10–4 357.1 ± 5.2
1–40 20 μM/Semax 1:1 10.5 ± 0.5 353.3 ± 5.6 462.0 ± 6.6 4.6·10–2 ± 1.8·10–3 21.7 ± 3.6
1–40 20 μM/Semax 1:5 10.5 ± 0.5 806.6 ± 4.3 865.4 ± 4.1 8.5·10–2 ± 2.2·10–3 11.8 ± 5.1
1–40 20 μM/Cu2+/Semax 1:1:1 3.7 ± 0.2 554.7 ± 2.1 706.2 ± 1.8 3.3·10–3 ± 1.2·10–4 303.0 ± 6.2
1–40 20 μM/Cu2+/Semax 1:1:5 5.8 ± 0.1 1407.7 ± 10.6 1635.0 ± 12.4 2.2·10–3 ± 2.3·10–4 454.5 ± 13.5
a

ThT curves were fitted by using the equation Inline graphic. Lag time was calculated as tlag = t1/2 – 2τ, and kapp was given by 1/τ. Results are the average of three independent experiments.