Table 4.
AUDIT cut-off score | Sensitivity | Specificity | PPV | NPV | LR+ | LR− | Youden’s Index | |
---|---|---|---|---|---|---|---|---|
Total | 5 | 0.96 | 0.70 | 56.6 | 97.6 | 3.20 | 0.06 | 0.66 |
6 | 0.95 | 0.77 | 62.2 | 97.3 | 4.05 | 0.07 | 0.71 | |
7 | 0.94 | 0.80 | 65.7 | 96.9 | 4.70 | 0.08 | 0.74 | |
8 | 0.94 | 0.84 | 69.8 | 97.0 | 5.67 | 0.08 | 0.77 | |
9 | 0.88 | 0.86 | 71.6 | 94.7 | 6.17 | 0.14 | 0.74 | |
10 | 0.83 | 0.89 | 75.0 | 92.8 | 7.35 | 0.19 | 0.72 | |
11 | 0.77 | 0.91 | 78.3 | 90.6 | 8.80 | 0.26 | 0.68 | |
12 | 0.76 | 0.91 | 78.0 | 90.2 | 8.68 | 0.27 | 0.67 | |
13 | 0.76 | 0.92 | 78.9 | 90.2 | 9.21 | 0.27 | 0.67 | |
14 | 0.71 | 0.92 | 77.9 | 88.7 | 8.70 | 0.31 | 0.63 | |
Area under the curve for men = 0.93 (95% CI = 0.90–0.97); SE = 0.019 | ||||||||
For male | 5 | 0.97 | 0.65 | 56.6 | 97.5 | 2.74 | 0.05 | 0.61 |
6 | 0.95 | 0.74 | 63.2 | 96.8 | 3.62 | 0.07 | 0.69 | |
7 | 0.95 | 0.76 | 65.5 | 96.9 | 3.98 | 0.07 | 0.71 | |
8 | 0.95 | 0.80 | 69.6 | 97.0 | 4.81 | 0.06 | 0.75 | |
9 | 0.91 | 0.81 | 69.7 | 95.7 | 4.84 | 0.11 | 0.73 | |
10 | 0.91 | 0.84 | 72.6 | 95.3 | 5.57 | 0.10 | 0.75 | |
11 | 0.83 | 0.85 | 72.7 | 91.2 | 5.59 | 0.20 | 0.68 | |
12 | 0.81 | 0.85 | 72.3 | 90.4 | 5.47 | 0.22 | 0.66 | |
13 | 0.81 | 0.86 | 73.4 | 90.5 | 5.83 | 0.22 | 0.67 | |
14 | 0.79 | 0.86 | 73.0 | 89.7 | 5.71 | 0.24 | 0.65 | |
Area under the curve for men = 0.93 (95% CI = 0.90–0.97); SE = 0.019 | ||||||||
For female | 5 | 0.94 | 0.76 | 56.7 | 97.6 | 3.95 | 0.07 | 0.71 |
6 | 0.94 | 0.80 | 60.7 | 97.8 | 4.67 | 0.07 | 0.74 | |
7 | 0.92 | 0.84 | 66.0 | 96.8 | 5.88 | 0.10 | 0.76 | |
8 | 0.92 | 0.87 | 70.2 | 96.9 | 7.16 | 0.10 | 0.79 | |
9 | 0.83 | 0.91 | 75.0 | 94.3 | 9.05 | 0.18 | 0.74 | |
10 | 0.69 | 0.95 | 80.6 | 90.4 | 12.62 | 0.32 | 0.64 | |
11 | 0.67 | 0.98 | 92.3 | 89.9 | 37.06 | 0.34 | 0.65 | |
12 | 0.58 | 0.98 | 92.3 | 89.9 | 32.39 | 0.42 | 0.57 | |
13 | 0.56 | 0.98 | 92.3 | 89.9 | 30.89 | 0.45 | 0.54 | |
14 | 0.42 | 1.00 | 91.3 | 87.7 | – | 0.58 | 0.42 | |
Area under the curve for women = 0.96 (95% CI = 0.92–0.99); SE: 0.016 |
PPV: positive predictive value; NPV: negative predictive value; LR: likelihood ratio; CI: confidence interval; SE: standard error.
Bold indicated an optimum cut-off point corresponding with diagnostic properties.