A, B. Western blot analysis for p-eIF2α, eIF2α, CHOP, ATF6α, cATF6α, and c-Jun in the sciatic nerve of 6-w-old Double cKO mice, Sel1L cKO mice, PERK cKO mice, and control mice. C. Real time-PCR analysis for XBP1s mRNA in the sciatic nerve of 6-w-old Double cKO mice, Sel1L cKO mice, PERK cKO mice, and control mice. D, E. Western blot analysis for p-eIF2α, eIF2α, CHOP, ATF6α, cATF6α, and c-Jun in the sciatic nerve of 16-w-old Double cKO mice, Sel1L cKO mice, PERK cKO mice, and control mice. F. Real time-PCR analysis for XBP1s mRNA in the sciatic nerve of 16-w-old Double cKO mice, Sel1L cKO mice, PERK cKO mice, and control mice. N = 4 animals. Statistical analyses were done with a 1-way ANOVA with a Tukeys posttest. Error bars represent SD, n.s. not significant, P < 0.05.