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. Author manuscript; available in PMC: 2022 Feb 18.
Published in final edited form as: Glia. 2020 Sep 16;69(2):489–506. doi: 10.1002/glia.23910

Figure 7. PERK inactivation in SCs did not affect developmental myelination in the PNS of Sel1L cKO mice. A-D.

Figure 7.

P0 immunostaining showed a comparable P0 immunoreactivity in the sciatic nerve of 6-w-old control mice, PERK cKO mice, Sel1L cKO mice, and Double cKO mice. E-H. Toluidine blue staining showed a comparable degree of myelination in the sciatic nerve of 6-w-old control mice, PERK cKO mice, Sel1L cKO mice, and Double cKO mice. I-O. EM analysis showed that the percentage of myelinated axons and the thickness of myelin were comparable in the sciatic nerve of 6-w-old control mice, PERK cKO mice, Sel1L cKO mice, and Double cKO mice. Scale bars: A-H, 20 μm; I-L, 5 μm. N = 4 animals. Statistical analyses were done with a 1-way ANOVA with a Tukeys posttest. Error bars represent SD, n.s. not significant.