Table 3.
Disease characteristics
| Disease characteristic | Total participants (N = 101) | Eosinophilic phenotype (n = 45) | Atopic 1 (n = 50) | Overlap 1 (eosinophilic/atopic 1) (n = 25) | Atopic 2 (n = 41) | Overlap 2 (eosinophilic/atopic 2) (n = 23) |
|---|---|---|---|---|---|---|
| Asthma duration, years (mean ± SD) | 17.6 ± 12.1 | 19.4 ± 12.8 | 15.6 ± 11.5 | 16.5 ± 12.7 | 16.6 ± 12.1 | 17.2 ± 12.9 |
| Number of severe exacerbations (mean ± SD) | 2.7 ± 4.2 | 2.4 ± 3.4 | 3.2 ± 4.0 | 2.9 ± 3.9 | 3.3 ± 4.3 | 3.0 ± 4.0 |
| Number of severe asthma exacerbations | ||||||
| 0 | 24 (24) | 9 (20) | 7 (14) | 3 (12) | 5 (12) | 2 (9) |
| 1 | 21 (21) | 11 (24) | 10 (20) | 5 (20) | 8 (20) | 5 (22) |
| 2 | 24 (24) | 12 (27) | 15 (30) | 10 (40) | 13 (32) | 10 (43) |
| 3 | 9 (9) | 6 (13) | 2 (4) | 1 (4) | 2 (5) | 1 (4) |
| > 3 | 23 (23) | 7 (16) | 16 (32) | 6 (24) | 13 (32) | 5 (22) |
| Asthma classification | ||||||
| Early-onset (< 12 years old at diagnosis) | 14 (14) | 9 (20) | 5 (10) | 4 (16) | 5 (12) | 4 (17) |
| Late-onset (≥ 12 years old at diagnosis) | 87 (86) | 36 (80) | 45 (90) | 21 (84) | 36 (88) | 19 (83) |
| History of atopy | ||||||
| No | 83 (82) | 35 (78) | 38 (76) | 16 (64) | 30 (73) | 15 (65) |
| Yes | 18 (18) | 10 (22) | 12 (24) | 9 (36) | 11 (27) | 8 (35) |
| Specific IgE available in medical records | ||||||
| No | 3 (3) | 2 (4) | 1 (2) | 1 (4) | 1 (2) | 1 (4) |
| Yes | 38 (38) | 14 (31) | 18 (36) | 10 (40) | 14 (34) | 9 (39) |
| Negative | 20/38 (53) | 5/14 (36) | 4/18 (22) | 2/10 (20) | 2/14 (14) | 1/9 (11) |
| Positive | 18 /38(47) | 9/14 (64) | 14/18 (78) | 8/10 (80) | 12/14 (86) | 8/9 (89) |
| Missing | 60 (59) | 29 (64) | 31 (62) | 14 (56) | 26 (63) | 13 (57) |
| Comorbidities | ||||||
| No | 35 (35) | 21 (48) | 20 (40) | 14 (56) | 18 (44) | 13 (57) |
| Yes | 65 (65) | 23 (52) | 30 (60) | 11 (44) | 23 (56) | 10 (43) |
| Missing | 1 (1) | 1 (2) | 0 (0) | 0 (0) | 0 (0) | 0 (0) |
Data are shown as n (%) unless otherwise indicated
SD standard deviation