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. 2022 Feb 18;17:23. doi: 10.1186/s13020-022-00579-7

Fig. 5.

Fig. 5

GXF down-regulated genes related to macrophages. A The expression of genes enriched in chemokine pathway. Gene expression level was measured in FPKM value. B The mRNA expression of CCL2, CCR2, CX3CL1, CX3CR1, CXCL16 and CXCR6 were evaluated by RT-qPCR. C The protein levels of CCL2 and CCR2 were evaluated by western blot. D Serum CCL2 level was evaluated by Elisa. The data are presented as means ± SEM (n = 4). #p < 0.05, ##p < 0.01 compared with control group; *p < 0.05 compared with CCl4 group