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. 2022 Feb 18;540:111063. doi: 10.1016/j.jtbi.2022.111063

Table 3.

Model parameters estimated by Bayesian inference based on daily deaths until 1 July 2020, assuming that after first lockdown Rc(t) begins a gradual return to the baseline R0 at a fixed rate (corresponding to T2=120 days in this case). Model selection based on maximum log-likelihood (LL) and Akaike information criterion (AIC). Best fitting models have lower AIC scores (bold). Infection fatality ratio, ϕ=0.9%. Herd immunity threshold (H) calculated from R0 and CV using formulas (14) or (22), as appropriate. T0 and T2 parameterise linear reduction and increase in transmissibility, respectively, before and after first lockdown (larger T lower slope; Fig. 6).

Heterogeneous susceptibility Heterogeneous connectivity Homogeneous
Median 95% CI Median 95% CI Median 95% CI
Common parameters
c1a 0.3133 (0.2989,0.3277) 0.3182 (0.3002,0.3419) 0.2358 (0.2291,0.2419)
ηb 15 {15} 15 {13,14,15} 17 {17}
νc 2.521 (2.369,2.653) 1.822 (1.681,2.011) 0



England
T0 -14.79 (-14.991,-13.922) -14.815 (-14.994,-13.952) -11.51 (-13.00,-10.17)
R0 3.438 (3.380,3.470) 3.451 (3.383,3.533) 3.017 (2.940,3.109)



H 15.46% (14.06%,17.15%) 14.97% (12.55%,17.29%) 66.85% (65.99%,67.84%)



Scotland
T0 -2.253 (-3.033,-2.010) -2.229 (-2.930,-2.007) -4.407 (-5.651,-4.017)
R0 3.308 (3.263,3.358) 3.319 (3.268,3.388) 3.234 (3.194,3.302)



H 15.01% (13.68%,16.74%) 14.53% (12.22%,16.77%) 69.08% (68.69%,69.71%)



Model selection
LL -951.7 -960.5 -3308
AIC 1917 1935 6627
a

Transmissibility reduction due to lockdown 1.

b

Difference between mean-time-to-death and mean-time-to-recovery (sampled from a continuous interval and reduced to the nearest integer before entering the model).

c

Coefficient of variation (CV).