Table 5. A comparison of the computational time required for the prediction of the test set used for the analysis in this paper.

Based on 4,226 proteins. DIAMOND and HMMScan calculations required for the input of Argot2, Argot2.5, and Wei2GO, were excluded from the computational times. No queue times for Argot2 and Argot2.5 were reported.

Method	Computational time (min)
DeepGOPlus	2
Argot2	173
Argot2.5	303
Wei2GO	4