Figure 1.

Identification of the hBM-MSCs and the derived exosomes. (a), expression of the surface marker proteins of hBM-MSCs determined by flow cytometry; (b), osteogenic and adipogenic differentiation abilities of hBM-MSCs examined by alizarin red staining (left) and oil red O staining (right), respectively; (c), shapes of the extracted particles observed under a TEM; (d), distribution of the particle size determined by nanoparticle tracking analysis; (e), protein levels of exosome-specific marker proteins CD81 and TSG101 determined by Western blot analysis. Three independent experiments were performed.