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. 2022 Jan 10;21(3):304–321. doi: 10.1080/15384101.2021.2020041

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© 2022 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited, and is not altered, transformed, or built upon in any way.

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Figure 3. — The impact of circ-PITX1 on NSCLC cells in vivo. H1975 cells were transfected along with circ-PITX1 overexpression plasmid or the vector (NC) and then subjected to in-vivo experiments. (a) The images of tumors in the two groups. b and c. The tumor volume (b) and weight (c) were calculated, **P < 0.01, ***P < 0.001 vs. the vector group. d and e. Western blot verified the protein levels of EMT markers (E-cadherin, Vimentin, and N-cadherin) and apoptosis-related proteins (Bax, Bcl-2, and c-Caspase3). **P < 0.01, ***P < 0.001 (vs.Vector group). n = 3.