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. 2022 Jan 10;21(3):304–321. doi: 10.1080/15384101.2021.2020041

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© 2022 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited, and is not altered, transformed, or built upon in any way.

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Figure 5. — Circ-PITX1 sponged miR-30e-5p. (a) miR-30e-5p was a candidate miRNA target of circ-PITX1 and ITGA6 as predicted by Starbase (http://starbase.sysu.edu.cn/). (b) The binding sites between miR-30e-5p and circ-PITX1, miR-30e-5p and ITGA6. c–f. Dual-luciferase reporter gene assay (c–d) and RIP assay (e–f) examined the binding correlation between miR-30e-5p and circ-PITX1, miR-30e-5p and ITGA6. (g). K-M plotter (http://kmplot.com/analysis/) revealed that a lower level of miR-30e-5p was relevant to the poorer survival of lung cancer patients. NS P > 0.05, ***P < 0.001.