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Circ-PITX1 exerted carcinogenic effects via the ITGA6/PI3K/Akt pathway. H1975 cells overexpressing circ-PITX1 or knocking down miR-30e-5p were handled with si-ITGA6 or dealt with the PI3K inhibitor (Wortmannin) for 24 hours, respectively. a and b: WB tested the expression of the ITGA6/PI3K/Akt pathway in H1975 cells. ns P > 0.05, ** P < 0.01, ***P < 0.001 (vs. Vector or NC-in group). && P < 0.01, &&&P < 0.001 (vs. circ-PITX1 or miR-30e-5p-in groups). n = 3.
