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. Author manuscript; available in PMC: 2022 Jul 1.
Published in final edited form as: Kidney Int. 2021 Apr 6;100(1):67–78. doi: 10.1016/j.kint.2021.03.024

Figure 2 |. Renal tubular epithelial cell (RTEC) repair following acute kidney injury (AKI).

Figure 2 |

On AKI, normally quiescent RTECs in G0 or G1 re-enter the cell cycle and proliferate. Slowing the G1/S transition aids in proper RTEC repair, but prolonged G2/M arrest leads to premature senescence and incomplete recovery. CDK, cyclin-dependent kinase.