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. Author manuscript; available in PMC: 2022 Feb 18.
Published in final edited form as: J Med Chem. 2021 Sep 2;64(18):13487–13509. doi: 10.1021/acs.jmedchem.1c00900

Figure 6.

Figure 6.

Efficacy study of ARD-2585 in the VCaP xenograft tumor model in SCID mice with enzalutamide included as the control. Seven mice were evaluated in each group. Animals were dosed daily via oral garage for 3 weeks. (a) Average tumor volume for each dosing group. (b) Percentage of mouse body weight change in each group.