Table 1.
Demographic, clinical, biochemical, and radiological features of all patients who underwent ERCP for suspected choledocholithiasis grouped by ERCP findings.
| Characteristics | ERCP-confirmed choledocholithiasis (n = 230) | Choledocholithiasis-negative ERCP (n = 40) | P-value |
|---|---|---|---|
| Age at ERCP (years), median (IQR) | 46 (32–57) | 47 (32–64) | 0.640 |
| Age >40 years, n (%) | 139 (60.4) | 23 (57.5) | 0.727 |
| Female, n (%) | 149 (64.8) | 19 (47.5) | 0.037 |
| Race/ethnicity, n (%) | 0.295 | ||
| White | 14 (6.1) | 6 (15.0) | – |
| Hispanic/Latino | 173 (75.2) | 26 (65.0) | – |
| Black | 3 (1.3) | 0 (0) | – |
| Asian | 7 (3.0) | 1 (2.5) | – |
| Other/unknown | 33 (14.4) | 7 (17.5) | – |
| BMI (kg/m2), median (IQR)a | 29.0 (26.0–34.0) | 29.1 (26.5–35.0) | 0.772 |
| BMI >30 kg/m2, n (%)a | 91 (40.6) | 16 (40.0) | 0.941 |
| Diabetes, n (%) | 30 (13.0) | 13 (32.5) | 0.002 |
| Fever, n (%) | 40 (17.4) | 11 (27.5) | 0.132 |
| Classic cholelithiasis risk factors (BMI >30 kg/m2, female, age >40 years), n (%) | |||
| 0 risk factor | 16 (7.1) | 5 (12.5) | 0.249 |
| 1 risk factor | 80 (35.7) | 17 (42.5) | 0.412 |
| 2 risk factors | 92 (41.1) | 13 (32.5) | 0.308 |
| 3 risk factors | 36 (16.1) | 5 (12.5) | 0.566 |
| History of cholecystectomy, n (%) | 54 (23.5) | 9 (22.5) | 0.893 |
| Peak bilirubin pre-ERCP (mg/dL), median (IQR) | 2.1 (0.5–3.7) | 2.1 (0.4–4.1) | 0.823 |
| Noninvasive imaging performed, n (%) | |||
| Ultrasound | 230 (100) | 40 (100) | – |
| CT | 99 (43.0) | 17 (42.5) | 0.949 |
| MRCP | 64 (27.8) | 13 (32.5) | 0.546 |
| EUS performed, n (%) | 12 (5.3) | 3 (8.1) | 0.487 |
| Maximum CBD diameter (mm) on noninvasive imaging, median (IQR) | 9.0 (6.0–11.0) | 8.0 (4.0–9.5) | 0.011 |
| Noninvasive imaging positive for choledocholithiasis, n (%) | 147 (63.9) | 13 (32.5) | <0.001 |
| Ultrasound positive for choledocholithiasis, n (%) | 82 (35.7) | 10 (25.0) | – |
| CT positive for choledocholithiasis, n (%) | 36 (15.7) | 1 (2.5) | – |
| MRCP positive for choledocholithiasis, n (%) | 57 (24.8) | 5 (12.5) | – |
Data are shown as n (%) or median (IQR).
Abbreviations: BMI, body mass index; CBD, common bile duct; CT, computed tomography; ERCP, endoscopic retrograde cholangiopancreatography; EUS, endoscopic ultrasound; MRCP, magnetic resonance cholangiopancreatography; IQR, interquartile range.
a
Six patients (2.2%) were missing BMI measurements.