Table 3.
Leisure-time physical activity and the risk of all-cause mortality stratified according to the presence of each cardiovascular disease.
| Patients | Deaths | Deaths/1,000 PYR | Adjusted HR (95% CI) | P value | Patients | Deaths | Deaths, /1,000 PYR | Adjusted HR (95% CI) | P value | |
|---|---|---|---|---|---|---|---|---|---|---|
| Stroke or TIA | With previous stroke or TIA | Without previous stroke or TIA | ||||||||
| Sedentary | 5,850 | 1,196 | 70.61 | Reference | 19,404 | 2,110 | 33.28 | Reference | ||
| 1–499 MET-min/week | 3,178 | 312 | 30.90 | 0.62 (0.54–0.70) | <0.001 | 13,381 | 916 | 20.49 | 0.77 (0.71–0.83) | <0.001 |
| 500–999 MET-min/week | 2,905 | 256 | 27.85 | 0.61 (0.53–0.70) | <0.001 | 13,055 | 817 | 18.85 | 0.77 (0.70–0.83) | <0.001 |
| 1,000–1,499 MET-min/week | 751 | 50 | 20.29 | 0.49 (0.37–0.66) | <0.001 | 4,014 | 195 | 14.32 | 0.65 (0.56–0.75) | <0.001 |
| ≥1,500 MET-min/week | 935 | 64 | 20.74 | 0.49 (0.38-0.63) | <0.001 | 4750 | 252 | 15.75 | 0.69 (0.60-0.78) | <0.001 |
| Heart failure | With previous heart failure | Without previous heart failure | ||||||||
| Sedentary | 3,936 | 776 | 67.34 | Reference | 21,318 | 2,530 | 36.76 | Reference | ||
| 1–499 MET-min/week | 2,154 | 283 | 42.40 | 0.82 (0.71–0.94) | 0.006 | 14,405 | 945 | 19.64 | 0.70 (0.64–0.75) | <0.001 |
| 500–999 MET-min/week | 1,825 | 218 | 37.92 | 0.84 (0.71–0.98) | 0.024 | 14,135 | 855 | 18.27 | 0.69 (0.64–0.75) | <0.001 |
| 1,000–1,499 MET-min/week | 487 | 38 | 24.05 | 0.56 (0.40–0.79) | <0.001 | 4,278 | 207 | 14.27 | 0.61 (0.53–0.70) | <0.001 |
| ≥1,500 MET-min/week | 580 | 44 | 23.42 | 0.54 (0.40–0.74) | <0.001 | 5,105 | 272 | 15.80 | 0.65 (0.57–0.74) | <0.001 |
| Myocardial infarction | With previous myocardial infarction | Without previous myocardial infarction | ||||||||
| Sedentary | 1,273 | 281 | 78.12 | Reference | 23,981 | 3,025 | 39.42 | Reference | ||
| 1–499 MET-min/week | 727 | 96 | 44.07 | 0.74 (0.58–0.94) | 0.016 | 15,832 | 1,132 | 21.51 | 0.72 (0.67–0.77) | <0.001 |
| 500–999 MET-min/week | 662 | 84 | 40.68 | 0.73 (0.57–0.94) | 0.015 | 15,298 | 989 | 19.60 | 0.71 (0.66–0.77) | <0.001 |
| 1,000–1,499 MET-min/week | 187 | 21 | 35.09 | 0.75 (0.48–1.18) | 0.215 | 4,578 | 224 | 14.46 | 0.59 (0.51–0.68) | <0.001 |
| ≥1,500 MET-min/week | 277 | 19 | 21.39 | 0.43 (0.27–0.68) | <0.001 | 5,408 | 297 | 16.32 | 0.65 (0.57–0.73) | <0.001 |
| Peripheral artery disease | With previous peripheral artery disease | Without previous peripheral artery disease | ||||||||
| Sedentary | 2,452 | 321 | 44.02 | Reference | 22,802 | 2,985 | 40.86 | Reference | ||
| 1–499 MET-min/week | 1,635 | 134 | 26.20 | 0.72 (0.59–0.89) | 0.002 | 14,924 | 1,094 | 22.02 | 0.72 (0.67–0.78) | <0.001 |
| 500–999 MET-min/week | 1,520 | 97 | 20.09 | 0.61 (0.49–0.78) | <0.001 | 14,440 | 976 | 20.46 | 0.73 (0.67–0.78) | <0.001 |
| 1,000–1,499 MET-min/week | 467 | 35 | 23.28 | 0.78 (0.54–1.12) | 0.173 | 4,298 | 210 | 14.40 | 0.58 (0.50–0.67) | <0.001 |
| ≥1,500 MET-min/week | 549 | 35 | 19.68 | 0.61 (0.43–0.87) | 0.006 | 5,136 | 281 | 16.23 | 0.63 (0.56–0.72) | <0.001 |
*
Adjusted for age, sex, body mass index, hypertension, diabetes mellitus, dyslipidemia, chronic kidney disease, chronic obstructive pulmonary disease, malignancy, smoking, alcohol, osteoporosis, hospital frailty risk score, Charlson comorbidity index score.
PYR, person-years; MET, metabolic equivalent task; HR, hazard ratio; CI, confidence interval.