Table 6.
Skin irritation results 24 h after the application.
| Animal | Group 1 |
Group 2 |
Group 3 |
|||
|---|---|---|---|---|---|---|
| Control |
Treated with F7 nanoemulsion |
Treated with conventional cream |
||||
| Erythema | Edema | Erythema | Edema | Erythema | Edema | |
| 1 | 0 | 0 | 0 | 1 | 1 | 1 |
| 2 | 0 | 0 | 1 | 0 | 1 | 0 |
| 3 | 0 | 0 | 1 | 1 | 0 | 1 |
| 4 | 0 | 0 | 2 | 0 | 1 | 1 |
| 5 | 0 | 0 | 1 | 1 | 1 | 1 |
| 6 | 0 | 0 | 0 | 1 | 1 | 1 |
| Average | 0 | 0 | 0.8 ± 0.6 | 0.7 ± 0.5 | 0.8 ± 0.4 | 0.8 ± 0.4 |
Group 1 was the control group, Group 2 animals were treated with nanoemulsion formulation F7, and group 3 animals were treated with conventional commercial cream (Lamisil). The numbers in the erythema scale are following: 0 none, 1 slight, 2 well defined, 3 moderate, 4 scar formation. In the edema scale the numbers are: 0 none, 1 slight, 2 well defined, 3 moderate, 4 severe.