Table 2.

Multivariate Cox regression analyses of variables.

Variables	β	Hazard ratio	95% CI (lower)	95% CI (upper)	p Value
Cystatin-C (mg/L)
≤1.1	ref	ref	–	–	–
>1.1	0.56	1.75	1.25	2.45	.001
Age (years)
≤65	ref	ref	–	–	–
>65	1.22	3.37	2.34	4.86	<.001
Potassium (mmol/L)
≤5	ref	ref	–	–	–
>5	0.38	1.46	1.14	1.87	.003
Homocysteine (umol/L)
≤12	ref	ref	–	–	–
>12	0.36	1.44	1.11	1.87	.006
CKD stage
Stage 3a	ref	ref	–	–	–
Stage 3b	0.03	1.03	0.77	1.38	.859
Stage 4	0.14	1.15	0.76	1.73	.512
Stage 5	1.32	3.74	1.27	10.98	.017
UACR (mg/g)
<30	ref	ref	–	–	–
30–299	0.58	1.78	1.36	2.33	<.001
≥300	0.66	1.91	1.27	2.85	.002

UACR: urinary albumin-to-creatinine ratio; CKD: chronic kidney disease.