Figure 5.

(A) ESR spectra corresponding to Panel I, the ·OH generated by the aptananozyme X in the presence of H₂O₂. Panel II, the ·AA radical generated by the aptananozyme X in the presence of ascorbate. Panel III, the mixture of ·AA and peroxy radical ·OOH generated by the aptananozyme X in the presence of the mixture of AA^–/H₂O₂. Panel IV, the mixture of ·AA and ·OOH generated by the aptananozyme X in the presence of the mixture of AA^–/H₂O₂ with added l-tyrosinamide. (B) Schematic suggested mechanistic cycle for the oxygenation of the Ar–H bond of l-tyrosinamide to catechol product by the Cu^II-functionalized C-dots aptananozymes.