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. 2022 Feb 18;14(2):e22371. doi: 10.7759/cureus.22371

Table 2. Procedural details (by breast).

* P-value is SimpliDerm vs. AlloDerm RTU

hADM: human cadaveric acellular dermal matrix; RTU: ready-to-use

  All Patients SimpliDerm AlloDerm RTU P-value*
  (N=181) (n=67) (n=114)  
Plane of expander/implant placement       <0.001
Prepectoral 149 (82.3%) 67 (100.0%) 82 (71.9%) --
Subpectoral 32 (17.7%) 0 (0.0%) 32 (28.1%) --
Intraoperative expander fill volume (mL), mean ± SD 327.7 ± 167.0 358.6 ± 191.3 309.5 ± 147.9 0.074
hADM perforated (versus not)       0.121
   Yes 76 (42.0%) 26 (38.8%) 50 (43.9%) --
   Unknown 26 (14.4%) 6 (9.0%) 20 (17.5%) --
Mastectomy Type       0.600
Skin-sparing 89 (49.2%) 31 (46.3%) 58 (50.9%) --
Nipple-sparing 91 (50.3%) 36 (53.7%) 55 (48.2%) --
Simple Mastectomy 1 (0.6%) 0 (0.0%) 1 (0.9%) --
Bilateral or Unilateral       0.396
Bilateral 148 (81.8%) 58 (86.6%) 90 (78.9%) --
Unilateral – left 17 (9.4%) 4 (6.0%) 13 (11.4%) --
Unilateral – right 16 (8.8%) 5 (7.5%) 11 (9.6%) --
Mastectomy Indication       0.812
Malignancy (therapeutic) 158 (87.3%) 59 (88.1%) 99 (86.8%) --
Prophylactic 23 (12.7%) 8 (11.9%) 15 (13.2%) --