Table 2.
Selective index values for doxorubicin hydrochloride (chemotherapy) and isolated compounds obtained from Fridericia platyphylla roots in human tumor cell lines after 48 h of treatment.
| U-251 | NCI-H460 | PC-3 | HT-29 | |
|---|---|---|---|---|
| Doxorubicin hydrochloride | UD | UD | 2.1 | UD |
| Brachydin E | 0.9 | 2.2 | 8.6 | 0.5 |
| Brachydin F | 1.4 | 0.7 | 1.8 | UD |
UD: undetermined. SI value greater than or equal to 2.0 was adopted as significant. Human cell lines: U-251 (glioblastoma), NCI-H460 (lung, non-small-cells), PC-3 (prostate), HT-29 (colon).