Table 1.

Hematological parameters and parameters of iron metabolism in intensive care COVID-19 patients compared to healthy donors and convalescent patients

	COVID patients	Healthy donors	convalescent patients	p value heathy vs. COVID	p value convalescent vs. COVID
Blood parameters	n = 27	n = 23	n = 54
hemoglobin [mmol/L]	6.96 ± 0.24	9.04 ± 0.14	8.99 ± 0.10	< 0.0001****	< 0.0001****
red blood cells [1012/L]	3.62 ± 0.13	4.87 ± 0.09	4.86 ± 0.05	< 0.0001****	< 0.0001****
hematocrit	0.33 ± 0.01	0.433 ± 0.01	0.436 ± 0.004	< 0.0001****	< 0.0001****
lymphocytes [109/L]	1.30 ± 0.54	2.09 ± 0.11	1.94 ± 0.08	0.035**	0.0027**
thrombocytes [109/L]	255.6 ± 20.78	259.4 ± 8.77	245.4 ± 5.43	0.709	0.329
monocytes [109/L]	0.61 ± 0.06	0.602 ± 0.04	0.550 ± 0.02	0.911	0.637
MCV [fL]	91.69 ± 1.40	89.57 ± 1.00	89.66 ± 0.44	0.322	0.340
MCH [pg]	31.15 ± 0.51	29.54 ± 0.40	29.90 ± 0.19	0.017*	0.021*
Blood gas parameters	n = 21	n = 6	n. m.
pO2 [kPa]	9.61 ± 0.69	14.78 ± 1.53		0.0004***
pCO2 [kPa]	4.54 ± 0.14	4.47 ± 0.32		0.598
pH	7.45 ± 0.008	7.42 ± 0.008		0.072
sO2 [%]	93.71 ± 0.88	98.08 ± 0.22		0.0016**
BI value [mmol/]	24.98 ± 0.61	22.87 ± 0.67		0.0418*
BE value [mmol/]	0.331 ± 0.80	−2.40 ± 1.00		0.0921
iron metabolism	n = 27	n = 23	n = 54
plasma ferritin [μg/L]	1082.7 ± 198.2	103.2 ± 20.2	131.4 ± 14.4	<0.0001****	<0.0001****
plasma iron [μmol/L]	5.21 ± 0.62	8.59 ± 0.65	9.33 ± 0.61	0.0004***	<0.0001****
plasma transferrin [g/L]	1.55 ± 0.07	2.60 ± 0.10	2.46 ± 0.61	<0.0001***	<0.0001****

Data are presented as mean ± standard error mean (SEM). Tests were performed two-sided. Mann-Whitney U-test was used for statistical analyses

The bold entries represent significant differences between the sample groups