Table 3.
Comparison of acute manifestations among Groups A (median 36 years, range 15–49 years) and B (median 64 years, range 50–85 years).
| AIP |
VP |
HCP |
TOTAL |
|||||
|---|---|---|---|---|---|---|---|---|
| A | B | A | B | A | B | A | B | |
| No. of patients | 32 | 33 | 11 | 29 | 1 | 1 | 44 | 63 |
| Follow up fertile years | 631 | 1221 | 269 | 1073 | 25 | 37 | 925 | 2331 |
| Asymptomatic (%) | 14 (44) | 7 (21) | 3 (27) | 13 (45) | 0 | 0 | 17 (39) | 20 (32) |
| p | 0.066 | 0.473 | 0.537 | |||||
| Symptomatic (%) | 18 (56) | 26 (79) | 8 (73) | 16 (55) | 1 | 1 | 27 (61) | 43 (68) |
| p | 0.052 | 0.312 | 0.461 | |||||
|
Acute symptoms solely (%) (no hospitalization) |
14 (44) | 4 (12) | 5 (45) | 4 (14) | 0 | 0 | 19 (43) | 8 (13) |
| p | 0.004* | 0.032* | 0.0004* | |||||
| No. of patients with hospitalization (%) | 4 (13) | 22 (67) | 3 (27) | 12 (41) | 1 | 1 | 8 (18) | 35 (56) |
| p | <0.001* | 0.486 | <0.001* | |||||
| No. of patients with recurrent attacks | 3 | 0 | 0 | 0 | 0 | 0 | 3 | 0 |
| Mean of acute attacks per hospitalized patient | 1 | 2.45 ± 1.74 | 1.33 ± 0.58 | 2.42 ± 1.31 | 1/1 | 1/1 | 1.2 ± 0.45 | 2.4 ± 1.58 |
| p | 0.422 | 0.064 | 0.002* | |||||
| Ratio of acute attacks per patient during fertile years1 | 0.0013± 0.0071 |
0.0442± 0.0496 |
0.0112± 0.0202 |
0.0270± 0.0396 |
– | – | 0.0049± 0.0137 |
0.0360± 0.0453 |
| p | <0.001* | 0.106 | <0.001* | |||||
| No. of patients treated with hematin | 3 | 2 | 2 | 7 | 1 | 0 | 62 | 93 |
1Follow up fertile years, 12–49 years of age; 2Hematin treatment during >100 attacks (1994 – 2015); 3Hematin treatment during 21 attacks (1980 – 2013).