Representative images of splinted wounds in mice on day 0 (i.e., immediately post-surgery) and on day 16 post-surgery after the removal of splints but before euthanasia. Wounds were treated with vehicle (5% PEG/saline), Tβrl (0.5 μmol), CMP (0.5 μmol), or Tβrl–CMP (0.5 μmol). In mice treated with Tβrl–CMP, 15 of the 16 wounds showed complete closure. Scale bars (blue) are separated by 1.0 mm.