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. 2021 Dec 6;477(3):649–661. doi: 10.1007/s11010-021-04290-3

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — Effect of miR-1246 on cell function of thyroid cancer cell lines. a RT-qPCR analysis of miR-1246 expression in the five cell lines. b RT-qPCR was utilized to verify the expression of miR-1246 mimics in TPC-1 and FTC-133 cells. c, d CCK-8 analysis of TPC-1 and FTC-133 cell proliferation. e Transwell analysis of migration and invasion of TPC-1 and FTC-133 cell lines (magnification, 200×). f Apoptosis level of TPC-1 and FTC-133 cells analyzed using FCM. *P < 0.05. RT-qPCR Real-time quantitative reverse transcription polymerase chain reaction, CCK-8 cell counting kit-8, FCM flow cytometry, NC negative control