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. 2021 Dec 28;59(2):1199–1213. doi: 10.1007/s12035-021-02653-x

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — Astrocyte and microglia changes in the subcortical white matter after irradiation a Representative images of GFAP-labeled cells in the subcortical white matter. b Quantification of GFAP-labeled cells in the subcortical white matter. c Representative Iba-1 immunostaining in the subcortical white matter. d Quantification of Iba-1–labeled cells in the subcortical white matter. e The protein levels of IL-1β, IL-2, IL-4, IL-6, IL-10, and KC in the cortical tissue at 5 days after irradiation as detected by Luminex assay in the Atg7 KO and WT pups. n = 7/group for the immunostaining and Luminex assay. *p < 0.05, ***p < 0.001.