Table 1.
Topic domain | All studies | Number of patients = number of studies | Cross-sectional/prospective studies | Case–control/retrospective study | Class of evidence |
---|---|---|---|---|---|
N | N | N | N | N | |
Screening and diagnosis of dysphagia in PD | 82 |
< 10 pts = 1 10–19 pts = 16 studies 20–50 pts = 28 studies > 50 pts = 37 studies |
58 | 24 |
4 Class I 4 Class II 18 Class III 56 Class IV |
QoL and prognosis of dysphagic patients with PD | 35 |
< 50 pts = 13 50–199 pts = 13 200–500 pts = 5 > 500 pts = 4 |
20 | 15 |
4 Class I 8 Class II 8 Class III 15 Class IV |
Studies were classified according to various descriptors, including topic domain, sample size, design, presence of diagnostic criteria of the syndrome and level of evidence according to the Classification of Evidence Schemes of the Clinical Practice Guideline Process Manual of the American Academy of Neurology 17. Each study was graded according to its risk of bias from Class I to Class IV (with I corresponding to the highest quality and IV to the lowest quality)