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. 2021 Aug 4;269(3):1610–1617. doi: 10.1007/s00415-021-10737-w

Table 2.

Comparison between multiple sclerosis patients subgroups: very minor-minor NBDs vs moderate-severe NBDs

MS patients (n = 1100) NBDs < 10 (n = 940, 83%) NBDs ≥ 10 (n = 160, 17%) p

Age, mean

years (SD)

43.7

(12.5)

47.2

(11.0)

0.0006b

Sex, M/W

Number (%)

325 (35%) /615 (65%) 109 (68%)/51 (32%) n.sa

Disease duration, mean

years (SD)

10.9

(8.9)

12.7

(7.7)

0.0002b

EDSS, median

(range)

2

0–9

4

(0–9)

 < 0.0001b

Phenotype RR/SP/PP

Number (%)

819 (87%)/83 (9%)/38 (4%) 108 (68%)/35 (22%)/17 (10%)  < 0.0001a

IPSS

mean, median

(SD, range)

8.9, 6

(8.9; 0–35)

21.5, 23

(9.9; 0–35)

 < 0.0001b

Bonferroni Method Correction

MS multiple sclerosis, NBDs Neurogenic bowel dysfunction score, SD standard deviation, M men, W women, EDSS Expanded Disability Status Scale, RR relapsing remitting, SP secondary progressive, PP primary progressive, IPSS International Prostatic Symptoms Score

aFisher test

bWilcoxon rank-sum test (Mann–Whitney)