Table 2.

Magnetic resonance imaging derived measures of HC, PD-non pRBD, and PD-pRBD females and males

	HC	PD-non pRBD	PD-pRBD	Group-by-sex test stat (P value)
Global atrophy
Cortical GM
F	30.11 (1.80)	29.39 (2.23)	30.03 (2.34)	1.577 (0.209)
M	29.39 (2.26)	28.15 (1.98)	28.15 (2.39)
Subcortical GM
F	3.69 (0.27)	3.63 (0.26)	3.66 (0.32)	1.773 (0.172)
M	3.54 (0.28)	3.51 (0.24)	3.41 (0.24)
Mean CTh, mm
F	2.44 (0.10)	2.42 (0.10)	2.41 (0.09)	0.017 (0.984)
M	2.41 (0.12)	2.39 (0.12)	2.38 (0.12)
Deep GM nuclei
Thalamus
F	0.460 (0.030)	0.465 (0.042)	0.456 (0.044)	0.741 (0.478)
M	0.443 (0.046)	0.441 (0.040)	0.429 (0.037)
Caudate
F	0.222 (0.028)	0.221 (0.027)	0.229 (0.022)	2.047 (0.131)
M	0.215 (0.024)	0.212 (0.025)	0.207 (0.024)
Putamen
F	0.303 (0.038)	0.294 (0.035)	0.296 (0.039)	0.995 (0.371)
M	0.290 (0.034)	0.286 (0.029)	0.275 (0.035)
Pallidum
F	0.126 (0.013)	0.127 (0.014)	0.131 (0.015)	3.084 (0.047)*
M	0.124 (0.015)	0.127 (0.013)	0.120 (0.015)
Hippocampus
F	0.279 (0.028)	0.267 (0.030)	0.272 (0.031)	0.802 (0.449)
M	0.257 (0.026)	0.252 (0.028)	0.247 (0.025)
Amygdala
F	0.110 (0.013)	0.103 (0.015)	0.108 (0.022)	2.397 (0.093)
M	0.110 (0.014)	0.105 (0.013)	0.101 (0.013)
Accumbens
F	0.032 (0.006)	0.031 (0.007)	0.034 (0.007)	1.618 (0.200)
M	0.031 (0.004)	0.030 (0.006)	0.030 (0.006)
Brainstem
F	1.382 (0.100)	1.412 (0.128)	1.412 (0.110)	2.393 (0.093)
M	1.390 (0.134)	1.375 (0.113)	1.338 (0.128)

Data are presented by groups as mean (SD). Volumetric variables are presented in ratios estimated by ((volume/eTIV) × 100). Two-way analyses of covariance (ANCOVA) with age as covariable, followed by Bonferroni post hoc tests, were used for all variables

CTh cortical thickness; F female; GM gray matter; HC healthy controls; M male; PD-non pRBD PD without probable RBD; PD-pRBD PD with probable RBD

*Differences between PD-non pRBD males and PD-pRBD males (P < 0.05)