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. 2022 Feb 18;12:2813. doi: 10.1038/s41598-022-06736-0

Figure 7.

Figure 7

Proposed biosynthetic pathway for actinomycin L. We propose that actinomycin L is formed through the reaction of anthranilamide (blue) with the 4-oxoproline moiety of actinomycin X2 prior to the condensation of two 4-MHA PPLs into the actinomycin L.