Table 2.
Family history.
| Family ID* | Criteria fulfilled | Index case cancer (sex, age at diagnosis) | Cancer family history Cancer type (sex, age at diagnosis) |
|---|---|---|---|
| 1 | Amsterdam | Colorectal M41 | Colorectal (M36, M34, F50, M?, M?), Hepatic (M49), Uterine (F50, F45), Urothelial (M?) |
| 2 | Amsterdam | Colorectal M38 | Colorectal (F40, F40) |
| 3 | Amsterdam-1 | Colorectal M35 | Colorectal (M68) |
| 4 | Amsterdam | Colorectal F41 | Colorectal (F45, M55, M40), Lung (M70, M?) |
| 5 | Amsterdam-1 | Colorectal F38 | Colorectal (M70), Breast (F50, F52) |
| 6 | Amsterdam-1 | Colorectal M54 | Colorectal (F42), Digestive (M50, M50, F42) |
| 7 | Amsterdam | Colorectal F46 | Colorectal (M68, M60) |
| 8 | Amsterdam | Colorectal F40 | Colorectal (M49, F?, M50, F69, M?), Gastric (F65), Uterine (F28) |
| 9 | Amsterdam | Colorectal M62 | Colorectal (M55, M67), Lung (M?), Sarcoma (M?), Bladder (M?), Central Nervous System (M?), Lymphoma (M?) |
| 10 | Amsterdam | Colorectal F34 | Colorectal (F28, M60), Polyps (F23), Ovary (F55), Bladder (M80) |
| 11 | Amsterdam | Colorectal F67 | Colorectal (M70, F62, F40), Oropharynx (M45) |
| 12 | Amsterdam | Endometrium F52 | Colorectal (M55, M30), “Cancer” (M?), Dysembryoplastic neuroepithelial tumour (M?), Langerhans cell histiocytosis (M?), Kidney (M50), Leukaemia (M68), Thyroid (F35, F35) |
| 13 | Amsterdam | Colorectal F37 | Colorectal (M54, F70), Central Nervous System (M45), Gastric (F60) |
| 14 | Amsterdam | Colorectal M54 | Colorectal (M43, F70), Skin (F55, M90) |
| 15 | Amsterdam-1 | Endometrium F57 | Colorectal (M54, F53, M74), Gastric (M?), Mouth (M?) |
| 16 | Amsterdam | Colorectal F74 | Colorectal (M70, M70, M81, F51, F?, F40), Renal (M30), Bladder (M81), Lung (M82), Skin (F74), Ovary (F?) |
| 18 | Amsterdam | Colorectal M56 | Colorectal (F30, F30), Kidney (M56), Breast (F63), “Cancer” (M16), Central Nervous System (M30, M42), maxillary sinus (F?) |
| 19 | Amsterdam | Colorectal F51 | Colorectal (M68, M32), Hodgkin Lymphoma (F55), “Cancer” (M58), Kidney (F66), Leukaemia (F7), Meningioma (F7) |
| 20 | Amsterdam-1 | Colorectal 68 | Colorectal (M90), Breast (F?), “Cancer” (F50), Thyroid (F25), Oesophageal (F60), |
| 22 | Amsterdam-1 | Colorectal F77 | Colorectal (F38), Lung (F47), Breast (F50) |
| 24 | Amsterdam | Colorectal M70 | Colorectal (M66, F45), Prostate (M70, M?) |
| 25 | Amsterdam-1 | Colorectal F55 | Colorectal (M50), Polyps (M?), Gastric (M52, F60), Epidermoid carcinoma (F55), Breast (F?, F38), Skin (F78, F?), “Cancer” (M60, M60), Prostate (M?), Uterine (F65) |
| 27 | Amsterdam | Colorectal F67 | Colorectal (F31, F78), Osteosarcoma (M?) |
| 28 | Amsterdam | Colorectal F46 | Colorectal (M24, F60) |
| 29 | Amsterdam-1 | Colorectal F41 | Liver (M51), Gastric (F?, F61, F?) |
| 30 | Amsterdam | Colorectal F40 | Colorectal (M58, M82) |
| 31 | Amsterdam | Colorectal F29 | Colorectal (M80, F42), Prostate (M80), Throat (M70, F?), Gastric (F?), Villous tubular adenoma (F?) |
| 32 | Amsterdam | Colorectal F37 | Colorectal (M50, F50), Polyps (F?), “Cancer” (M50) |
| 33 | Amsterdam | Colorectal M37 | Colorectal (F60, F?, M?), Basocellular (F60, F?), Breast (F50), Nasal (F?) |
| 34 | Amsterdam-2 | Colorectal M58 | Colorectal (M58, M60), Lymphoma (M80), Stomach (M80) |
| Families with multiple members analyzed | |||
| 17 | Amsterdam-1 | Colorectal M45 | Colorectal (M51 (17.1)), Bladder (M45), Polyps (F?, F?), “Cancer” (F?, F?, F?) |
| 21 | Amsterdam | Colorectal M49 | Colorectal (M50, M72 (21.1), F49 (21.2)), Cerebral (M65, M58), Breast (F?), Polyps (F?), Multiple Myeloma (F?), “Cancer” (F?, F?, F?) |
| 23 | Amsterdam-1 | Endometrium F58 | Colorectal (M33 (23.1), F?), Polyps (M?, M?, M?, F?), Myelodysplastic syndrome (M?), Breast (F70, F45, F50), Thyroid (F50), Melanoma (F50) |
| 26 | Amsterdam-2 | Colorectal F42 | Colorectal (F51 (26.1)), Endometrial (F47), Cervical (F42), “Cancer” (M?, M?) |
*Patient ID follows the family ID. Families with more than one individual analysed have a second number separated by a dot (.) (highlighted in bold); M = Male, F = Female; ? = Unknown age at diagnosis.