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. Author manuscript; available in PMC: 2023 Dec 1.
Published in final edited form as: Exp Clin Psychopharmacol. 2021 Aug 19;30(6):797–808. doi: 10.1037/pha0000519

Table 1:

Correlates of Opioid PDM and Co-Ingestion Status in Young Adults (18-25 Years of Age)

No Past-Year Opioid
PDM
Past-Year but not
Past-Month Opioid
PDM
Past-Month PDM
without Alcohol Co-
Ingestion
Past-Month PDM
with Alcohol Co-
Ingestion
Sample Size 65,176 3,472 839 410
Physical Health Correlates OR (95% CI) OR (95% CI) OR (95% CI) OR (95% CI)
 Self-reported Fair or Poor Health 1.00 (reference) 1.55 (1.35-1.78)*** 2.14 (1.66-2.75)*** 2.13 (1.46-3.12)***
 Currently Uninsured 1.00 (reference) 1.02 (0.90-1.17) 1.08 (0.87-1.34) 1.40 (0.97-2.03)
 Past-year Emergency Department Use 1.00 (reference) 1.80 (1.64-1.98)*** 1.63 (1.33-2.01)*** 2.21 (1.77-2.76)***
 Past-year Hospitalization 1.00 (reference) 1.76 (1.53-2.03)*** 1.88 (1.42-2. 49)*** 2.41 (1.75-3.31)***
 Past-year Sexually Transmitted Disease 1.00 (reference) 2.48 (2.09-2.93)*** 2.51 (1.93-3.26)*** 4.84 (3.23-7.26)***+
Mental Health Correlates OR (95% CI) OR (95% CI) OR (95% CI) OR (95% CI)
 Past-year Mental Health Treatment 1.00 (reference) 2.13 (1.90-2.37)*** 2.19 (1.67-2.87)*** 3.36 (2.55-4.45)***+
 Past-year Major Depression 1.00 (reference) 2.54 (2.26-2.87)*** 2.22 (1.66-2.95)*** 2.57 (1.87-3.52)***
 Past-year Serious Psychological Distress 1.00 (reference) 2.61 (2.39-2.84)*** 2.41 (1.99-2.92)*** 2.98 (2.31-3.85)***
 Past-year Suicidal Ideation 1.00 (reference) 2.95 (2.64-3.28)*** 3.05 (2.44-3.81)*** 3.54 (2.75-4.55)***
Substance Use Correlates OR (95% CI) OR (95% CI) OR (95% CI) OR (95% CI)
 Past-month Binge Alcohol Use 1.00 (reference) 2.68 (2.44-2.96)*** 1.56 (1.28-1.90)*** 21.91 (12.82-37.44)***++
 Past-month Marijuana Use 1.00 (reference) 4.30 (3.95-4.67)*** 5.57 (4.59-6.77)*** 12.53 (9.33-16.83)***++
 Past-month Nicotine Dependence 1.00 (reference) 3.90 (3.47-4.59)*** 4.68 (3.91-5.60)*** 8.58 (6.81-10.81)***++
 Past-month Non-Marijuana Illicit Drug Use 1.00 (reference) 6.65 (5.80-7.64)*** 7.88 (6.11-10.15)*** 30.23 (21.24-43.03)***++
 Any past-year DSM-IV SUD 1.00 (reference) 6.58 (5.91-7.32)*** 7.63 (6.25-9.30)*** 18.33 (14.50-23.19)***++
 Multiple past-year SUDs 1.00 (reference) 10.51 (9.01-12.26)*** 12.39 (9.94-15.46)*** 33.79 (27.00-42.29)***++

Data Source: 2015-19 National Survey on Drug Use and Health (NSDUH)

PDM = Prescription Drug Misuse; OR = Odds Ratio; 95% CI = 95% confidence interval of the point prevalence estimate; SUD = Substance Use Disorder

Bonferroni-corrected significant differences from the reference group denoted as

*

p ≤ 0.008

**

p ≤ 0.0017

***

p ≤ 0.00017 (adjusted for six comparisons).

+

denotes significantly different from past-year but not Past-Month PDM

++

denotes significantly difference from all other categories (both p < 0.008).