Table 2:

Comparison of patient characteristics and fluid dynamics prior to administration of albumin by those who received albumin ≤12 hours and >12 hours post burn. Values are shown as mean ± SD or median (IQR) as indicated.

	Albumin started ≤ 12 hours N=118	Albumin started >12 hours N=135	P value
Age (years)	49.8 ± 17.4	46.5 ± 15	0.11
% TBSA burn	39.3 ± 20.0	34.0 ± 18.0	0.01
% full thickness burn	18.5 ± 29.5	10.0 ± 22.5	0.01
Inhalation Injury	28 (23.7)	16 (11.9)	0.01
Cumulative Crystalloids (mL)	5014.9 ± 3327.7	10894.4 ± 6190.4	<0.0001
Cumulative Crystalloids (mL/kg/%TBSA burn)	1.51 ± 0.98	3.53 ± 1.81	<0.0001
Urine (mL/kg/hour)*	0.45 (0.70)	0.64 (0.49)	<0.0001
Input:Output Ratio**	0.49 (1.04)	0.34 (0.32)	0.01

% full-thickness burn, % TBSA burn, Urine (mL/kg/hour), and Input:Output Ratio were compared with a Wilcoxon-Mann-Whitney Test. Age, Cumulative Crystalloids (mL), and Cumulative Crystalloids (ml/kg/% TBSA burn) were compared with a two-sample t-test. Inhalation Injury was evaluated with a Chi-Square Test.

^*Note: Urine (mL/kg/hour) did not include pre burn-center urine output.

^**Note: For 21 patients, albumin was started upon admission or did not have any urine output before being administered albumin. They are listed as ‘missing’ and not included in the analysis.