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. 2022 Feb 18;12:2831. doi: 10.1038/s41598-022-06838-9

Table 2.

Denomination and prevalence of multimorbidity patterns found in COVID-19 patients based on sex and age and their age-adjusted odds ratios (aOR) of infection severity compared with chronic patients without multimorbidity.

15–64 years 65–79 years  ≥ 80 years
Pattern name (N, prevalence %) Severity aOR (95% CI) Pattern name (N, prevalence %) Severity aOR (95% CI) Pattern name (N, prevalence %) Severity aOR (95% CI)
Women Cardiometabolic (4,205, 21.4%) 1.85 (1.43–2.41) Cardiometabolic (673, 19.1%) (99% diabetes mellitus) 1.97 (1.15–3.49) Cardiometabolic (541, 13.1%) 1.29 (0.85–1.96)
Menstrual-dysphoric (2,204, 11.1%) 1.48 (1.08–2.02) Thyroid-cardiometabolic (515, 14.6%) (no diabetes mellitus) 1.55 (0.86–2.79) Psychogeriatric (1,011, 24.5%) 1.06 (0.71–1.58)
Mental health (2,046, 10.3%) 0.90 (0.63–1.29) Osteoporotic-cardiovascular (70, 19.9%) (no diabetes mellitus) 1.20 (0.67–2.14) Mental health (753, 18.3%) 1.32 (0.87–1.98)
Upper respiratory (1,987, 10.0%) 1.13 (0.79–1.62) Mental health (823, 23.3%) (no diabetes mellitus) 1.58 (0.90–2.80) Non-specific (1,679, 40.8%) 1.05 (0.71–1.55)
Non-specific (4,810, 24.3%) 1.35 (1.02–1.77) Non-specific (663, 18.8%) (no diabetes mellitus) 1.22 (0.68.2.18)
Control group (4,528, 22.8%) Control group (152, 4.3%) Control group (135, 3.3%)
Men Hypertension-obesity (1,585, 10.4%) 1.60 (1.25–2.05) Cardiometabolic I (421, 12.3%) (99% obesity) 1.76 (1.18–2.62) Cardiometabolic I (546, 24.6%) 1.28 (0.96–1.70)
Cardiometabolic (1,136, 7.4%) 1.43 (1.14–1.80) Cardiometabolic II (619, 18.1%) (no obesity) 1.23 (0.84–1.81) Cardiometabolic II (590, 26.5%) 1.28 (0.96–1.70)
Mental Health (1,911, 12.5%) 1.35 (1.06–1.74) Cardiometabolic III (637, 18.6%) (no obesity) 1.41 (0.96–2.06) Arthrosis-cardiometabolic (444, 20.0%) 1.28 (0.96–1.71)
Upper respiratory (1,446, 9.5%) 1.30 (0.97–1.75) Prostatic-cardiometabolic (699, 20.4%) (18% obesity) 1.30 (0.89–1.89) Prostatic (233, 10.5%) 1.30 (0.92–1.84)
Headache (1,949, 12.8%) 1.24 (0.93–1.64) Arthrosis-cardiometabolic (394, 11.5%) (no obesity) 1.20 (0.80–1.82) Dementia (348, 15.6%) 1.42 (1.04–1.94)
Non-specific (2,274, 14.9%) 1.18 (1.03–1.60) Non-specific (416, 12.1%) (no obesity) 1.28 (0.85–1.93)
Control group (4,973, 32.6%) Control group (241, 7.0%) Control group (63, 2.8%)

In bold letters, patterns with statistically significant age-adjusted odds ratios of infection severity; Control group: chronic patients without multimorbidity; CI: confidence interval.