Table 3.

Relationship between Cognalyzer^® version 1 psychoactive effect (PE) levels (log transformed) and the modified Drug Effects Questionnaire (DEQ) scores in the PP population (n = 41)

Drug Effects Questionnaire vs. Cognalyzer® V1 PE levels
Variables	DEQ question 1—feel			DEQ question 2—high			DEQ question 3—dislike
	Coefficient	Standard error	p value	Coefficient	Standard error	p value	Coefficient	Standard error	p value
(Intercept)	9.11	1.15	< 0.001	9.06	1.19	< 0.001	2.5	1.48	0.093
Cognalyzer® V1 THC level	0.38	0.23	0.102	0.26	0.22	0.25	0.38	0.27	0.167
Time 0.5 h	− 0.64	0.32	0.045	− 0.6	0.31	0.052	− 0.54	0.38	0.156
Time 1 h	− 1.15	0.36	0.002	− 1.24	0.35	< 0.001	− 0.4	0.43	0.357
Time 1.5 h	− 2.57	0.34	< 0.001	− 2.98	0.33	< 0.001	− 0.77	0.4	0.058
Time 2 h	− 3.82	0.36	< 0.001	− 4.14	0.35	< 0.001	− 0.77	0.43	0.077
Time 2.5 h	− 4.56	0.37	< 0.001	− 4.85	0.36	< 0.001	− 1.04	0.44	0.018
Time 3 h	− 5.38	0.37	< 0.001	− 5.58	0.35	< 0.001	− 1.37	0.43	0.002
Time 3.5 h	− 6.35	0.39	< 0.001	− 6.65	0.37	< 0.001	− 1.25	0.46	0.007
Time 4 h	− 7.03	0.4	< 0.001	− 7.05	0.39	< 0.001	− 1.86	0.48	< 0.001
Age	− 0.05	0.03	0.153	− 0.05	0.04	0.146	0	0.04	0.976
Gender-male	0.09	0.48	0.851	0.14	0.49	0.779	− 0.64	0.62	0.309
Cognalyzer® PE level:time 0.5 h	− 0.23	0.3	0.453	0.03	0.29	0.914	− 0.67	0.36	0.063
Cognalyzer® PE level:time 1 h	0.24	0.34	0.473	0.31	0.33	0.349	0.07	0.4	0.863
Cognalyzer® PE level:time 1.5 h	− 0.25	0.27	0.356	− 0.31	0.26	0.236	− 0.37	0.32	0.257
Cognalyzer® PE level:time 2 h	− 0.53	0.29	0.068	− 0.53	0.28	0.06	− 0.44	0.34	0.203
Cognalyzer® PE level:time 2.5 h	− 0.46	0.29	0.114	− 0.43	0.28	0.127	− 0.67	0.35	0.054
Cognalyzer® PE level:time 3 h	− 0.45	0.31	0.147	− 0.42	0.3	0.162	− 0.74	0.37	0.046
Cognalyzer® PE level:time 3.5 h	− 0.78	0.33	0.019	− 0.71	0.32	0.027	− 0.72	0.39	0.069
Cognalyzer® PE level:time 4 h	− 0.78	0.3	0.009	− 0.63	0.29	0.028	− 0.72	0.35	0.043

Drug Effects Questionnaire vs. Cognalyzer® V1 PE levels
Variables	DEQ question 4—like			DEQ question 5—more of drug
	Coefficient	Standard error	p value	Coefficient	Standard error	p value
(Intercept)	6.94	1.66	< 0.001	1.46	1.77	0.411
Cognalyzer® V1 THC level	0.95	0.35	0.007	0.06	0.3	0.831
Time 0.5 h	− 0.23	0.48	0.64	− 0.05	0.41	0.913
Time 1 h	− 0.53	0.54	0.332	0.18	0.47	0.701
Time 1.5 h	− 1.2	0.51	0.021	− 0.31	0.44	0.479
Time 2 h	− 2.08	0.55	< 0.001	− 0.63	0.47	0.185
Time 2.5 h	− 2.8	0.56	< 0.001	− 0.72	0.48	0.134
Time 3 h	− 3.48	0.55	< 0.001	− 0.48	0.47	0.316
Time 3.5 h	− 4.76	0.59	< 0.001	− 0.46	0.5	0.366
Time 4 h	− 5.37	0.61	< 0.001	− 1.1	0.52	0.036
Age	− 0.01	0.05	0.841	− 0.01	0.05	0.876
Gender-male	1.12	0.69	0.114	1.47	0.74	0.055
Cognalyzer® PE level:time 0.5 h	− 0.77	0.46	0.094	− 0.23	0.39	0.56
Cognalyzer® PE level:time 1 h	− 0.52	0.51	0.31	0.33	0.44	0.451
Cognalyzer® PE level:time 1.5 h	− 0.75	0.41	0.071	− 0.13	0.35	0.705
Cognalyzer® PE level:time 2 h	− 1.26	0.44	0.004	− 0.22	0.38	0.562
Cognalyzer® PE level:time 2.5 h	− 1.13	0.44	0.011	− 0.53	0.38	0.162
Cognalyzer® PE level:time 3 h	− 1.06	0.47	0.025	− 0.34	0.4	0.392
Cognalyzer® PE level:time 3.5 h	− 1.89	0.5	< 0.001	− 0.3	0.43	0.49
Cognalyzer® PE level:time 4 h	− 1.77	0.45	< 0.001	− 0.63	0.39	0.104