Table 2.

Research priorities in postpartum preeclampsia

Gaps in Knowledge	Proposed Methods and Specific Questions
Prospective determination of disease incidence and risk factors	Prospective postpartum BP measurement following uncomplicated deliveries.
	Telehealth and remote monitoring may be useful to address this gap.
In-depth understanding of etiology and pathophysiology	Prospective biomarker identification both prior to disease onset and at the time of diagnosis.
	Placenta pathology to evaluate features of vascular malperfusion, if available
	Biorepositories may assist in answering these questions.
Development of evidence-based management algorithms.	Prospective studies examining outcomes with varying treatment.
	Priority should be given to the need for magnesium postpartum as well as the role of specific antihypertensive agents and routine use of diuretics. Determining optimal threshold for acute treatment and targets (for PP). Priority should also be given to development of the most effective strategies for patient and provider education surrounding postpartum preeclampsia recognition and diagnosis.
Understanding risk of recurrence and future pregnancy risk as well as optimal management.	Large-scale multi-center studies will likely be needed to address these questions.
	Specific questions include the use of low-dose aspirin in future pregnancies and postpartum prophylaxis with home BP monitoring or diuresis in future pregnancies.
Assessing future risk to maternal health.	Clear definitions and classification will aid in determination of future cardiovascular risk.
	Of particular interest is risk of heart failure among women with postpartum preeclampsia, which is known to be increased among women with preeclampsia with antepartum-onset.