ST6Gal-1 causes decreased apoptosis in rectal cancer cells after chemoradiation.A, caspase 3/7 Glo assay 24 h after treatment with chemoradiation revealed increased apoptosis, represented by fold change of relative light units, after treatment in the ST6Gal-1 KD cells compared with CV cells (SW620 and SW837, N = 5, ∗ indicates p < 0.05). B, Western blot for cleaved caspase 3 in SW620 and SW837 cells 24 h after treatment revealed increased cleaved caspase 3, indicating apoptosis, in the KD cells after chemoradiation compared with CV cells (N = 3).