Table 2.
Dose and duration of colistin and subsequent management of all four cases
| Case 1 | Case 2 | Case 3 | Case 4 | |
|---|---|---|---|---|
| Pathogen | P. aeruginosa | A. baumanii | K. pneumoniae | A. baumanii |
| Site of growth | Blood | Tracheal | Blood | Blood |
| Colistin dose | 3 MU tds | 3 MU tds | 3 MU tds | 1 MU tds |
| Appearance of dyselectrolytemia (days) | 12 | 7 | 7 | 8 |
| Management | ||||
| Potassium (mEq/day) | 240 | 240 | 160 | 240 |
| Magnesium (g/day) | 6 | 5 | 4 | 1.5 |
| Days between cessation of colistin and resolution of dyselectrolytemia | 12 | 4 | 5 | 12 |
| Spironolactone (dose) | 50 mg BD | — | — | 50 mg OD |