Table 4.

ROC analysis and AUC for various diagnostic tests across time period

	Period 1		Period 2		Period 3		Period 4
Parameters	AUC	Sig	AUC	Sig	AUC	Sig	AUC	Sig
IG#	0.565 (0.466–0.664)	0.195	0.809 (0.727–0.892)	0.000 (S)	0.859 (0.788–0.931)	0.000 (S)	0.887 (0.820–0.954)	0.000 (S)
IG%	0.490 (0.388–0.592)	0.838	0.818 (0.739–0.896)	0.000 (S)	0.823 (0.749–0.897)	0.000 (S)	0.882 (0.818–0.945)	0.000 (S)
Procalcitonin	0.525 (0.425–0.624)	0.619	0.597 (0.498–0.695)	0.054	0.828 (0.756–0.900)	0.000 (S)	0.864 (0.794–0.933)	0.000 (S)
Lactate	0.416 (0.321–0.511)	0.093	0.493 (0.395–0.592)	0.896	0.704 (0.614–0.794)	0.000 (S)	0.709 (0.621–0.797)	0.000 (S)

(S) denotes significant (p <0.001) p values